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Rubtsov Group Page

Igor V. Rubtsov, Assistant Professor
Ph.D., 1992, Institute of Chemical Physics, Russian Academy of Science
Office: Room 504 Israel Building
Telephone: (504) 862-8943
Email: irubtsov@tulane.edu

Discipline:
Physical Chemistry, Biophysics, Multidimensional IR Spectroscopy

Research Interest:
We are developing novel methods for measuring 3D structures of molecules in solution at physiological temperatures.  We are also interested in applying these new structural methods and target the mechanisms of protein and enzyme biological functioning.  Three-dimensional structure arrangement and dynamics of structural fluctuations play key roles in enzymes functioning.  Nonlinear femtosecond spectroscopy methods, such as two-dimensional IR spectroscopy, permits measuring quick snapshots of the structural distribution of molecules in solution.  

Dual-frequency RA 2DIR rephasing absolute-value spectrum of the PBN compound.

Selected Publications

1.  Naraharisetty, S. G., Kasyanenko, V. M. and Rubtsov, I. V. (2008). Bond connectivity measured via relaxation-assisted two-dimensional infrared spectroscopy. J. Chem. Phys. (2008) in press.

2.  Kurochkin, D. V.; Naraharisetty, S. G.; Rubtsov, I. V., Relaxation-assisted 2D IR spectroscopy method.  Proc. Natl. Acad. Sci. U.S.A., (2007) 104, 14209-14214 (2007).

3.  Naraharisetty, S. G.; Kurochkin, D. V.; Rubtsov, I. V., C-D Modes as structural reporters via dual-frequency 2DIR spectroscopy. Chem. Phys. Lett., (2007), 437(4-6), 262-266.

4.  Kurochkin, D. V.; Naraharisetty, S. G.; Rubtsov, I. V., Relaxation-assisted 2D IR using weak vibrational modes.  Springer Series in Chemical Physics, 2007, 88, 344-346.

5. Zhang, T.; Rubtsov, I. V.; Nakajima, H.; Aono, S.; Yoshihara, K.,  Effect of Mutation on the Dissociation and Recombination Dynamics of CO in Transcriptional Regulator CooA: A Picosecond Infrared Transient Absorption Study,  (2006) Biochemistry,  45(30),  9246-9253

6.  Russo, R. M.; Mele, E. J.; Kane, C. L.; Rubtsov, I. V.; Therien, M. J.; Luzzi, D. E.   One-dimensional diffusion-limited relaxation of photoexcitations in suspensions of single-walled carbon nanotubes.    Physical Review B: Condensed Matter and Materials Physics  (2006),  74(4),  041405/1-4.

7.  Kurochkin, D. V., Naraharisetty, S. G., Rubtsov, I. V., Dual-Frequency 2D IR on Interaction of Weak and Strong IR Modes, J. Phys. Chem. A, 2005, 109, 10799-10802.

8.  Rubtsov, I. V., Kumar, K., Hochstrasser, R. M. Dual-frequency 2D IR photon echo of a hydrogen bond. Chem. Phys. Lett., 2005, 402(4-6), 439-443.

9.  Noy, D. N., Discher, B. M., Rubtsov, I. V., Hochstrasser, R. M., Dutton, P. L.  Design of amphiphilic protein maquettes: enhancing maquette functionality through binding of extremely hydrophobic cofactors to lipophilic domains.  Biochem., 2005, 44(37), 12344-12354.

10.  Rubtsov, I. V., Russo, R. M. Albers, T. Deria, P. Lussi, D. E. Therien, M. J. Visible and near-infra red excited-state dynamics of single-walled carbon nanotubes. Appl. Phys. B, 2004, 79(7), 1747-1751.

11.  Rubtsov, I. V., Redmore, N. P., Hochstrasser, R. M., Therien, M. J. Interrogating conformationally dependent electron transfer dynamics via ultrafast visible pump / IR probe spectroscopy, J. Am. Chem. Soc., 2004, 126(9), 2684-2685.

12.  Rubtsov, I. V., Kang, Y. Redmore, N. P., Allen, R. M. Beratan, D. N., Therien, M. J. Degree of charge transfer in ground and charge separated states revealed by ultrafast visible pump / IR probe spectroscopy, J. Am. Chem. Soc., 2004, 126(16), 5022-5023.

13.  Rubtsov, I. V., Wang, J., Hochstrasser, R. M. Dual frequency 2D-IR heterodyned photon-echo of the peptide bond, Proc. Natl. Acad. Sci. USA, 2003, 100(10), 5601-5606.

14.  Rubtsov, I. V., Wang, J., Hochstrasser, R. M. Dual Frequency 2D-IR Spectroscopy of the Amide-A and Amide-I Modes in Peptides. J. Chem. Phys. 2003, 118, 7733-7736.

15.  Rubtsov, I. V., Wang, J., Hochstrasser, R. M. Vibrational coupling between amide-I and amide-A modes revealed by femtosecond two-color infrared spectroscopy. J. Phys. Chem. A, 2003, 107(18), 3384-3396.

16.  Rubtsov, I. V., Susumu, K., Rubtsov, G. I., Therien, M. J., Ultrafast singlet excited-state polarization in electronically asymmetric ethyne-bridged bis[(porphinato)zinc(II)] complexes. J. Am. Chem. Soc., 2003, 125(9), 2687-2696.

 
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